Super Resolution Direct Optical Imaging through Transparent Microspheres, a New Optical Imaging Approach for Biomedical Science Main Body
|30 November 2011
|12:30 - 14:00
|What is it:
You are warmly invited to our next BII Seminar 'Super Resolution Direct Optical Imaging through Transparent Microspheres, a New Optical Imaging Approach for Biomedical Science' on Wednesday 30th November 2011. This event commences with lunch at 12.30pm in Room 2.220, University Place, and is followed by the seminar itselt at 1pm.
To attend this seminar please complete the on-line registration form: http://www.mhs.manchester.ac.uk/surveys/TakeSurvey.aspx?PageNumber=1&SurveyID=l8KM8o93
Introduction: Due to the optical diffraction limit, the theoretical ultimate resolution of an optical microscope is 200 nm for visible light illumination. For biomedical imaging, florescent microscopy is commonly used to indirectly visualize structural features below the diffraction limit, through selectively activating the imbedded florescent particles injected into biological materials. In this presentation, a new approach utilizing coupled transparent microspheres is linked to a standard optical microscope for direct optical imaging. A record 50 nm resolution has been demonstrated. The application of the microsphere optical microscopy (MOM) in the imaging of cells, bacteria and virus is demonstrated. Some of the small sized biomedical materials such as viruses have been observed for the first time with direct optical imaging without the use of florescent dyes.
Professor Lin Li, Director of Laser Processing Research Centre (LPRC), Photon Science Institute, obtained a PhD degree from Imperial College in 1989 in laser engineering, and has been active in optical engineering research for over 26 years with over 450 publications and 40 patents, mainly in the area of laser processing of materials and laser beam interaction with materials. He has been elected as Fellow of Laser Institute of America, a Director of Laser Institute of America and Fellow of Institute of Engineering and Technology. He is member of Editorial Boards of 9 interactional journals. He is one of the inventors of the microsphere optical microscopy.
Dr. Zengbo Wang, Lecturer in laser micro/nano engineering in the LPRC, obtained a BSc and MSc in Physics in China and a PhD degree from National University of Singapore in laser engineering. He has over 80 publications in laser beam interaction with materials and internationally known for modeling of nano-scale optical phenomena. He is one of the inventors of the microsphere optical microscopy.
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