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PRODID:-//Columba Systems Ltd//NONSGML CPNG/SpringViewer/ICal Output/3.3-
 M3//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20150529T145529Z
DTSTART:20150609T120000Z
DTEND:20150609T130000Z
SUMMARY:Moving the hands of the clock
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}b4r-ia9qepr
 l-stgfae
DESCRIPTION:This seminar is part of the Future Leaders in Sensory and Com
 putational Neuroscience series - showcasing the best up and coming resea
 rchers in the field.                                                    
                                                                         
                                                                         
                                                                         
                                                                         
                                                                         
                                                                         
                                                                         
                                                                         
                                                                         
                                Abstract: Most aspects of physiology and 
 behaviour\, including the sleep-wake cycle display 24-hour rhythms (circ
 adian rhythms)\, and these rhythms are being increasingly recognised for
  their role in maintaining health and wellbeing. Circadian rhythms are d
 riven by a molecular oscillator found in many cell types in the body\, w
 hich are maintained in synchrony by a master circadian pacemaker located
  in the suprachiasmatic nuclei (SCN). The SCN is synchronised to the daw
 n-dusk cycle by photic input from the retina\, and my research focusses 
 on elucidating the mechanisms by which light entrains the molecular cloc
 k.  My talk will summarise our recent work in this area\, including char
 acterising retinal pathways that signal light information to the circadi
 an system and transcriptional pathways activated by light within the SCN
 . Based on these results\, we have extended our findings to the identifi
 cation of novel and tractable signalling pathways by which the clock may
  be targeted for pharmacological modulation.
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
LOCATION:4.005\, AV Hill Building\, Manchester
END:VEVENT
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