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Centre for Primary Care Seminar – Dr Peter Knapp – University of York – The TRECA study (Trials Engagement in Children and Adolescents)

Dates:19 February 2019
Times:13:00 - 14:00
What is it:Seminar
Organiser:Faculty of Biology, Medicine and Health
Who is it for:University staff, Current University students
Speaker:Dr Peter Knapp
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In this seminar I will present details of the NIHR-funded TRECA study - it should be of interest to researchers and academics working in trials, or with children & teenagers, or with an interest in information for patients.

Randomised controlled trials are the best way to determine the effectiveness and safety of healthcare interventions. However, there are very few healthcare trials involving children and adolescents meaning that important clinical decisions are based on evidence extrapolated from trials involving adults. A key barrier to paediatric trials is the high rate of patient (or parent) refusal to participate, though it is possible that this could be reduced by improving the quality of information about trial participation. Current printed information sheets have been widely criticised for being too long, technical and lacking in visual appeal. Multimedia information (MMI) resources involving text, audio, video and animations have the potential to better inform children and adolescents and their parents about trials, potentially leading to their increased engagement in healthcare trials.

The TRECA study (Trials Engagement in Children and Adolescents) has two phases:

Phase 1 – Development: We developed two MMI templates, influenced by qualitative work with relevant stakeholders (children and adolescents with long-term conditions, parents, clinicians). The MMIs were ‘user tested’ for their ability to inform patients/parents and then revised.

Phase 2 – Evaluation: The MMIs are being embedded in six host clinical trials which are recruiting children and adolescents. We are testing the impact of the MMIs on decision making by comparing rates of trial recruitment (whether patients decide to participate) and retention (whether they stay on the trial) between participants who receive the standard participant information sheet alone; the MMIs alongside the standard participant information sheets; and those who receive the MMIs alone. We are also assessing quality of decision-making by questionnaire.

Speaker

Dr Peter Knapp

Role: Senior Lecturer

Organisation: University of York

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Seminar Room, Fifth Floor
Williamson Building
Manchester

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Dr Salwa Zghebi, on behalf of the CPC Seminar Series Organising Committee

salwa.zghebi@manchester.ac.uk

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