SPECIAL DMDS Divisional Seminar – Venue: Michael Smith Lecture Theatre
Dear All,
Benjamin Fairfax from Oxford will give a presentation at our DMDS Divisional Seminar on 18th November 2019 (see advert below).
If you would like to meet with Benjamin after his seminar, please let me know Sebastien Viatte (sebastien.viatte@manchester.ac.uk)
Benjamin's current work focuses upon 2 areas:
i) Genetics & Epigenetics of gene expression in monocytes
ii) Dissecting response to immune checkpoint blockade in cancer - this second area involves much of the TCR mapping and he has made a number of findings outside the arena of cancer.
Best regards, Sebastien Viatte
Date: Monday 18 November 2019
Time: 1.00pm
Venue: Michael Smith Lecture Theatre
SPECIAL DMDS Divisional Seminar:
Benjamin Fairfax – “Deciphering the response to Immune Checkpoint Blockade in patients: insights from analysis of the TCR repertoire.”
Welcome Clinical Fellow, Hon. Consultant Medical Oncologist & Principal Investigator, Department of Oncology, MRC Weatherall Institute for Molecular Medicine, University of Oxford, UK.
Here are some of Benjamin’s most important publications:
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele.
Al-Mossawi H, Yager N, Taylor CA, Lau E, Danielli S, de Wit J, Gilchrist J, Nassiri I, Mahe EA, Lee W, Rizvi L, Makino S, Cheeseman J, Neville M, Knight JC, Bowness P, Fairfax BP.
Nat Commun. 2019 Oct 8;10(1):4575. doi: 10.1038/s41467-019-12393-1.
PMID: 31594933
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
Fairfax BP, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight JC.
Science. 2014 Mar 7;343(6175):1246949. doi: 10.1126/science.1246949.
PMID:24604202
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles.
Fairfax BP, Makino S, Radhakrishnan J, Plant K, Leslie S, Dilthey A, Ellis P, Langford C, Vannberg FO, Knight JC.
Nat Genet. 2012 Mar 25;44(5):502-10. doi: 10.1038/ng.2205.
PMID:22446964
