Events at The University of Manchester
  • University home
  • Events
  • Home
  • Exhibitions
  • Conferences
  • Lectures and seminars
  • Performances
  • Events for prospective students
  • Sustainability events
  • Family events
  • All Events

IDSAI Seminar: Professor Claudio Angione

Dates:2 May 2023
Times:14:00 - 15:00
What is it:Seminar
Organiser:Digital Futures
Who is it for:Early years, External researchers, Adults, Alumni
See travel and contact information
Add to your calendar

Other events

  • In category "Seminar"
  • By Digital Futures

Speaker: Claudio Angione, Professor of Artificial Intelligence at Teesside University (TU)

Title: Combining machine learning and metabolic modelling approaches to characterise the cell phenotype

In recent biomedical research, deep learning has been widely used for the exploitation of omics data when predicting the cell phenotype, suffering however from a lack of biological interpretability. In parallel, constraint-based mathematical modelling of metabolism has gained popularity due to its scope and flexibility, enabling mechanistic insights into the genotype-phenotype-environment relationship within cells.

These two computational frameworks have mostly been used in isolation, having distinct research communities associated with them. However, their complementary characteristics and common mathematical bases make them particularly suitable to be combined. I will describe how machine learning can be combined with constraint-based modelling, discuss the mathematical and practical aspects involved, and show several applications in biotechnology and biomedicine.

Instead of applying machine learning to omics data directly, we propose a multi-view approach merging experimental omics data and model-generated predictions, based on known biochemistry. This architecture can contribute with disjoint information towards biologically-informed and interpretable machine learning, including key mechanistic information in an otherwise biology-agnostic learning process.

Travel and Contact Information

Find event

 

Contact us

  • +44 (0) 161 306 6000

Find us

The University of Manchester
Oxford Rd
Manchester
M13 9PL
UK

Connect with the University

  • Facebook page for The University of Manchester
  • X (formerly Twitter) page for The University of Manchester
  • YouTube page for The University of Manchester
  • Instagram page for The University of Manchester
  • TikTok page for The University of Manchester
  • LinkedIn page for The University of Manchester

  • Privacy /
  • Copyright notice /
  • Accessibility /
  • Freedom of information /
  • Charitable status /
  • Royal Charter Number: RC000797
  • Close menu
  • Home
    • Featured events
    • Today's events
    • The Whitworth events
    • Manchester Museum events
    • Jodrell Bank Discovery Centre events
    • Martin Harris Centre events
    • The John Rylands Library events
    • Exhibitions
    • Conferences
    • Lectures and seminars
    • Performances
    • Events for prospective students
    • Sustainability events
    • Family events
    • All events