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Advances in Biosciences Seminar - Dr Mattias Soller, Birmingham University - Title: Keeping RNA regulation in shape for health

Dates:21 November 2023
Times:13:00 - 14:00
What is it:Seminar
Organiser:Faculty of Biology, Medicine and Health
Who is it for:University staff
Speaker:Dr Mattias Soller
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  • By Faculty of Biology, Medicine and Health

Matthias Soller received his PhD in 1997 at the University of Zurich, Switzerland. He then moved to Brandeis University, Boston, USA to study RNA binding proteins and their function in alternative splicing regulation in axon guidance, synaptic plasticity and neuronal degeneration using Drosophila as a model system with Kalpana White.

In 2006, Matthias Soller started his own research group in the School of Biosciences at the University of Birmingham, UK. He continued to work on post-transcriptional control of gene-expression in the brain, adaptive immunity and cancer as well as in the regulation of behaviour. The Soller laboratory has been pioneering in studying mRNA methylation in a genetic model organism. Fundamental contributions to the discovery of biological functions of mRNA internal m6A methylation in the regulating gene expression include an essential role in sex determination and dosage compensation. More recently, the Soller laboratory has generated the first animal knock-out for methylation of mRNA cap-adjacent nucleotides and discovered an essential role in local translation at synapses relevant to reward learning.

Speaker

Dr Mattias Soller

Role: Associate Professor

Organisation: University of Birminham

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Michael Smith Lecture Theatre
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Yasmin Moore

01613067104

yasmin.moore@manchester.ac.uk

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