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 M3//EN
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CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20190307T085039Z
DTSTART:20190308T120000Z
DTEND:20190308T130000Z
SUMMARY:Manchester Infection Seminar Series 2019 - Unexpected roles for h
 erpes simplex virus structural proteins in RNA metabolism
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}e9m-jp9tmhg
 k-vh7ood
DESCRIPTION:Professor Gillian Elliott \nDept of Microbial Sciences\, Univ
 ersity of Surrey\nCell biology of herpes simplex virus (HSV) infection\n
 \nProfessor Gill Elliott will join us on Friday 12 noon (AV Hill 1.006) 
 to deliver a talk: Unexpected roles for herpes simplex virus structural 
 proteins in RNA metabolism\n \nGill is a serving member of the MRC Infec
 tions & Immunity Board (IIB) whose research focuses on the cell biology 
 of herpes simplex virus (HSV) infection and uses a combination of live c
 ell studies\, fluorescently tagged viruses\, virus genetics\, siRNA depl
 etion\, and biochemical assays to pinpoint critical molecules - both vir
 al and cellular - as potential targets for antiviral intervention. If yo
 u would like to meet with Gill\, or join us for lunch on Friday\, please
  contact Elaine Bignell directly elaine.bignell@manchester.ac.uk and use
  the header Gill Elliott appointment.\n \nUnlike the majority of human v
 iruses\, HSV establishes lifelong latent infection (in sensory neurons)\
 , and is reactivated periodically to produce new disease and infectivity
 . Reactivated HSV has a major impact on human health throughout the worl
 d. Apart from oral cold sores and genital herpes\, reactivated HSV is al
 so the leading cause of infectious blindness in the developed world\, an
 d the major viral cause of encephalitis that can often be fatal. \nLike 
 all viruses\, HSV exploits pre-existing cellular activities in its repli
 cation.  Gill’s work aims to determine how HSV hijacks cellular machiner
 y to coordinate the assembly of its large\, complex particles\, with a p
 articular interest in how HSV utilises the cellular secretory pathway to
  direct the process of assembly\; how the individual virus structural mo
 lecules interact as the new particle is built\; where in the cell these 
 interactions occur\; and which cellular molecules are crucial to this pr
 ocess. \n\n
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
LOCATION:Room 1.006\, AV Hill Building\, Manchester
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