BEGIN:VCALENDAR
PRODID:-//Columba Systems Ltd//NONSGML CPNG/SpringViewer/ICal Output/3.3-
 M3//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20240108T145129Z
DTSTART:20240112T110000Z
DTEND:20240112T120000Z
SUMMARY:The 695th Lord Mayor's Lectures: Computational Medicine and Digit
 al Twins Improving Medical Care\, with Prof Alex Frangi
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}f2h9-lqxpgt
 bi-v3pu86
DESCRIPTION:Prof Alex Frangi\, Director of the Christabel Pankhurst Insti
 tute\, and the Bicentennial Turing Chair for Computational Medicine\, wi
 ll speak at the Lord Mayor’s Lectures Series next week about computation
 al medicine and digital twins in healthcare.\n\nNovel medical technologi
 es are being introduced at unprecedented rates\, demanding scientific ev
 idence of their safety and efficacy at an unprecedented pace to ensure p
 atient safety and benefit. With success in both in-vitro/in-vivo studies
 \, products are tested on clinical trials assessing use in humans. Predi
 cting low-frequency side effects has been difficult because such side ef
 fects may not become apparent until many patients adopt the treatment. W
 hen medical devices fail at later stages\, financial losses can be catas
 trophic. Testing on many people is costly\, lengthy\, and sometimes impl
 ausible (e.g.\, paediatric patients\, rare diseases\, and underrepresent
 ed or hard-to-reach ethnic groups). \n\nComputational Medicine underpins
  In-silico trials (IST)\, i.e.\, computer-based trials of medical produc
 ts performed on populations of digital twins (aka virtual patients). Com
 puter models/simulations are used to conceive\, develop\, and assess dev
 ices with the intended clinical outcome explicitly optimised from the ou
 tset (a-priori) instead of tested on humans (a-posteriori). This will in
 clude testing for potential risks to patients (side effects) and exhaust
 ively exploring medical device failure modes before being tested in huma
 n clinical trials. In-silico evidence is still consolidating but is pois
 ed to transform how health and life sciences R&D and regulations are con
 ducted. UK can take a leadership position in in-silico trials\, which wo
 uld cement its position as a global leader in health and life sciences\,
  help drive the UK economy and provide UK citizens with early access to 
 innovative health products. \n\nThe Rt Hon the Lord Mayor Alderman Profe
 ssor Michael Mainelli is pleased to extend an invitation to all to parti
 cipate in “Knowledge Miles: The Lord Mayor's Lectures”\, an online webin
 ar series exploring the connections of the Square Mile and how its knowl
 edge clusters are addressing diverse global challenges.\n\nLink to regis
 ter: https://register.gotowebinar.com/register/2743880080838287968
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
END:VEVENT
END:VCALENDAR