Dr. Nasreen Akhtar: Keeping ‘abreast’ of mammary gland tissue morphogenesis
MRC Come & See are delighted to announce Dr Nasreen Akhtar as the fourth speaker in our virtual public health keynote series.
How the cells inside our bodies assemble to form organs with recognizable shapes and structures remains a fundamental question in biology. Exploring the mechanisms of tissue architecture is of central importance both for controlling cancerous growth and in future technologies geared toward organ replacement strategies.
Dr Nasreen Akhtar is a lecturer in Developmental Cell Biology at the University of Sheffield, and she uses the mammary gland as a model system to understand how tissues form and remodel through the action of mechanical forces and signalling from the extracellular matrix. Her recent work has uncovered some unexpected roles for the cytoskeletal regulator Rac1 in tissue remodelling and mammary gland reversibility in the post-lactating phase. She will also discuss how the b1-integrin mechanoreceptor regulates tissue shape and polarity. Her lab uses a combination of in vivo genetic deletion mouse models, primary mammary organoids and 3D imaging to address experimental questions.
The keynote is open to everybody, both within and outside the University, and will take place via Zoom.
Register for the lecture, feel free to share the event with friends, and colleagues who may be interested!
The zoom details will be sent to you before the event when you register with the link.
Looking forward to seeing you soon,
The MRC DTP student committee
Dr Nasreen Akhtar
Role: Lecturer in developmental cell biology
Organisation: University of Sheffield
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