Bruno Martins - Round the clock: single-cell dynamics of circadian processes in cyanobacteria
| Dates: | 21 October 2020 |
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| Times: | 13:00 - 14:00 |
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| What is it: | Seminar |
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| Organiser: | Department of Mathematics |
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| Who is it for: | University staff, External researchers, Current University students |
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| Speaker: | Bruno Martins |
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(via Zoom)
Join us for this seminar by Bruno Martins (Warwick) as part of the North West Seminar Series in Mathematical Biology and Data Sciences. Details of the full series can be found here https://www.cms.livjm.ac.uk/APMSeminar/
Abstract: Circadian clocks are regulatory circuits that generate 24-h rhythms of gene expression in anticipation to daily cycles of sunlight. Substantial progress has been made in understanding how cells generate and sustain these rhythms in a variety of organisms. However, our knowledge of how the clock is coupled to other circuits and cellular processes inside the cell, what types of dynamics arise from this coupling, and what biological functions it serves is still incomplete. In this talk, I will use the cyanobacterium Synechococcus elongatus as a model system to address those questions through a combination of single-cell time-lapse microscopy and mathematical modelling. I will show how coupling the clock to other pathways can give rise to rich dynamic behaviours. Examples include frequency doubling in oscillating gene expression or the 24-h modulation of the cell division rate – distributing cells into subpopulations following different cell size control rules and providing a template to understanding the complex interdependency between the clock, the environment and gene expression.
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Speaker
Bruno Martins
Role: Assistant Professor
Organisation: University of Warwick
Travel and Contact Information
