Social Statistics Seminars: Dr. Stephen Burgess (Cambridge)
| Dates: | 19 March 2024 |
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| Times: | 14:00 - 15:30 |
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| What is it: | Seminar |
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| Organiser: | School of Social Sciences |
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| Who is it for: | University staff |
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| Speaker: | Dr. Stephen Burgess |
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Dr. Stephen Burgess (Cambridge) will be presenting “Mendelian randomization: How can genetics guide the design of clinical trials?”.
The event will take place in Williamson Building, Room 2.05
Abstract: When considering whether an exposure is a causal risk factor for an outcome, evidence from randomized trials is reliable but typically slow or impractical to gather, whereas evidence from conventional observational studies is often unreliable, as it is subject to bias from confounding and reverse causation. Mendelian randomization is an example of a quasi-experimental approach: it is analogous to a randomized trial, but relies on nature doing the randomization for us. Mendelian randomization can be implemented rapidly for a range of exposures to provide insights about causal relationships that can prioritize or deprioritize exposures for further investigation. This talk with discuss methods and examples that enable detailed Mendelian randomization analyses to inform the design of trials so that collection of randomized evidence can be as informative as possible: enabling trial interventions to target the right mechanism in the right population group at the right time.
Speaker
Dr. Stephen Burgess
Role: Investigator Scientist at Medical Research Council (MRC) Biostatistics Unit
Organisation: University of Cambridge
Travel and Contact Information
Find event
2.05
Williamson Building
Manchester
