BEGIN:VCALENDAR
PRODID:-//Columba Systems Ltd//NONSGML CPNG/SpringViewer/ICal Output/3.3-
 M3//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20140124T150609Z
DTSTART:20140204T160000Z
DTEND:20140204T170000Z
SUMMARY:Tumour adaptability in endocrine treated breast cancer
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}pbw-hqtl10p
 x-sl3o1s
DESCRIPTION:In breast cancer\, a significant number of endocrine treated 
 patients develop recurrent disease.  The ability of a tumour to adapt an
 d evade endocrine therapy\, though clinically recognised\, remains poorl
 y understood.  Our group use discovery and molecular studies along with 
 in vivo and clinical models to investigate signalling pathways central t
 o tumour adaptability. We have observed that endocrine therapy can direc
 tly contribute to metastasis in resistant tumours and that extracellular
  matrix signalling network are switched on at metastatic sites following
  prolonged endocrine treatment.
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
LOCATION:Holt Major\, Paterson Institute\, Wilmslow Road\, Manchester\, M
 20 4BX
END:VEVENT
END:VCALENDAR