Ed Morrisey - Studying the fixation and spread of mutations in human epithelium by combining modelling and deep learning
|Dates:||12 October 2020|
|Times:||14:00 - 15:00|
|What is it:||Seminar|
|Organiser:||Department of Mathematics|
|Who is it for:||University staff, External researchers, Current University students|
Join us for this seminar by Ed Morrisey (Oxford) as part of the North West Seminar Series in Mathematical Biology and Data Sciences. Details of the full series can be found here https://www.cms.livjm.ac.uk/APMSeminar/
Abstract: Most adult tissues are stem cell fuelled. Not only do these stem cells provide new cells to the tissue, they also slowly replace each other leading to a form of competition. It is currently thought that it is during this replacement process that mutations can spread and, in some cases, eventually lead to cancer. I will describe how combining Deep Learning for tissue analysis with stochastic modelling of stem cell dynamics we can study how mutations are seeded in human epithelium, how they spread and whether particular mutations make the stem cells more fit.
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Role: MRC WIMM Group Leader
Organisation: University of Oxford
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