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PRODID:-//Columba Systems Ltd//NONSGML CPNG/SpringViewer/ICal Output/3.3-
 M3//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20241004T141425Z
DTSTART:20241009T120000Z
DTEND:20241009T130000Z
SUMMARY:Elin Falla -- A mathematical model centred on aphid vector feedin
 g behaviour has implications for plant host manipulation by plant viruse
 s [ONLINE]
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}ruw-m1ut3ts
 6-vcsm02
DESCRIPTION:Join us for this seminar by Elin Falla (Cambridge) as part of
  the North West Seminar Series in Mathematical Biology and Data Science.
  More details about the joint series can be found here https://northwest
 seminars.great-site.net/ . \n\nThe talk will be hosted by the University
  of Liverpool and available to watch via zoom. Please contact carl.whitf
 ield@manchester.ac.uk or mdomijan@liverpool.ac.uk for the link\, or sign
  up to the mailing list.\n\nTitle: A mathematical model centred on aphid
  vector feeding behaviour has implications for plant host manipulation b
 y plant viruses\n\nAbstract: Plant viruses threaten global food security
  and are often horizontally transmitted by arthropod vectors. Non-persis
 tently transmitted (NPT) plant viruses are characterised by a short viru
 s retention time in the vector and are transmitted almost exclusively by
  aphids\, attached transiently to the aphid’s stylet (mouthparts) and ac
 quired and inoculated via brief epidermal probes. Many NPT viruses can a
 lter their host plant’s phenotype to change the behaviour of aphids in a
  way that often optimises virus transmission. Mechanistic epidemiologica
 l models of this phenomenon have historically overlooked a key feature o
 f NPT virus transmission: probing or feeding on a plant often causes an 
 aphid to lose the virus. A recent model by Donnelly et al. (2019) captur
 es this behaviour\, but assumes an aphid is guaranteed to lose the virus
  after probing one healthy plant. Very few experimental studies have exp
 lored the number of consecutive plants an aphid can probe before virus l
 oss\, but the limited evidence suggests this assumption is not justified
 . Our new compartmental mathematical model includes the ability of an ap
 hid to probe\, and potentially inoculate\, consecutive plants\, while al
 so linking aphid feeding behaviour to virus transmission. We use our nov
 el model structure to explore the effect of NPT virus-induced host pheno
 types on epidemic outcomes. We find that previous models underestimate t
 he benefit of an “attract-and-deter” phenotype\, where the virus induces
  increased aphid attraction to the infected plant but deters them from p
 rolonged feeding. Our results also highlight the importance of character
 ising NPT virus longevity within the aphid during probing\, as allowing 
 for consecutive infective probes increases the effectiveness of virus ma
 nipulation\, with implications for NPT virus epidemic prediction and con
 trol.\n\nR. Donnelly\, N. J. Cunniffe\, J. P. Carr\, and C. A. Gilligan.
  Pathogenic modification of plants enhances long-distance dispersal of n
 onpersistently transmitted viruses to new hosts. Ecology\, 100(7):e02725
 \, 2019.\n\nThis is joint work with Prof. Nick Cunniffe. \n\nTo subscrib
 e to the mailing list for this event series\, please send an e-mail with
  the phrase “subscribe math-lifesci-seminar” in the message body to list
 serv@listserv.manchester.ac.uk
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
LOCATION:Online
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