Chromatin Dynamics in Seasonal Timing
|Starts:||12:00 5 Feb 2014|
|Ends:||13:00 5 Feb 2014|
|What is it:||Seminar|
|Organiser:||Faculty of Life Sciences|
|Who is it for:||Current University students, University staff|
|Speaker:||Professor Caroline Dean, OBE, FRS|
The study of how plants monitor seasons in order to regulate the transition to reproduction has led us into the dissection of two conserved mechanisms that link antisense transcription with chromatin dynamics. These pathways quantitatively modulate expression of the flowering repressor locus FLC via different environmental and developmental cues.
Prolonged cold up-regulates FLC antisense transcription and this is linked to quantitative accumulation of Polycomb silencing of FLC. Developmental cues lead to alternative 3’ processing of FLC antisense transcripts that trigger chromatin changes resulting in transcriptional down-regulation. The talk will describe our latest understanding of these conserved mechanisms, how they intersect to give robust and quantitative regulation of this developmental regulator and how these mechanisms have been modulated during adaptation.
Professor Caroline Dean, OBE, FRS
Organisation: John Innes Centre, Norwich
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