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MIB Seminar - Dr Megan Wright - “Chemical tools to label proteins in living cells”

Dates:8 February 2023
Times:12:00 - 13:00
What is it:Seminar
Organiser:Manchester Institute of Biotechnology (MIB)
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Dr Megan Wright (University of Leeds)

Abstract: Chemical probes are powerful tools for dissecting biological mechanism in living systems and exploring drug targets. In my lab we are developing chemical tools to label proteins in their native cellular environment. For example we design specific photoaffinity probes to label proteins of interest to image and study their function in cells, and elaborate bioactive small molecules into probes with covalent or photocrosslinking groups to define their protein targets via chemical proteomic workflows. We work with other scientists to tackle questions in many biological contexts, including plants, cancer and inflammation. In this talk I will focus on our work developing tools to explore host-microbe interactions and to identify the targets of novel anti-parasitic compounds.

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