BEGIN:VCALENDAR
PRODID:-//Columba Systems Ltd//NONSGML CPNG/SpringViewer/ICal Output/3.3-
 M3//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20201019T160839Z
DTSTART:20201026T140000Z
DTEND:20201026T150000Z
SUMMARY:Laleh Haghverdi - Reconstruction of gene expression dynamics from
  scRNA-seq data in cell differentiation
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}w12n-kfw9n2
 zj-c8j8ni
DESCRIPTION:(via Zoom)\nJoin us for this seminar by Laleh Haghverdi (Max 
 Delbruck) as part of the North West Seminar Series in Mathematical Biolo
 gy and Data Sciences. Details of the full series can be found here https
 ://www.cms.livjm.ac.uk/APMSeminar/\n\nAbstract: Measuring gene activitie
 s at the single cell level is important in studies where cell heterogene
 ities are of particular interest rather than population averages. It is 
 intuitive to consider all biological processes originate from such singl
 e-cell level heterogeneous responses and only in a collective response o
 f several cells larger scale observable features arise. The reconstructi
 on of cell lineage trajectories from single-cell RNA-seq data allows us 
 to resolve temporal expression dynamics of several genes from snapshot c
 ollected data\, which are not accessible in time-laps experiments. The t
 emporal order of gene activities in return\, can provide new insights in
 to the gene regulatory networks governing cell differentiation. Does a s
 napshot of cell states sampled from the non-equilibrium system of cell d
 ifferentiation provide adequate information for reconstruction of the fu
 ll dynamical process? What other information are we still missing for th
 is purpose? In my talk I will give an overview of existing approaches to
  this question covering our contribution on reconstruction of “diffusion
  pseudotime”.\n\nTo subscribe to the mailing list for this event series\
 , please send an e-mail with the phrase “subscribe math-lifesci-seminar”
  in the message body to listserv@listserv.manchester.ac.uk
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
END:VEVENT
END:VCALENDAR