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CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20231206T153306Z
DTSTART:20231211T140000Z
DTEND:20231211T150000Z
SUMMARY:Andrea Cairoli -- Physical principles of Drosophila abdomen morph
 ogenesis during metamorphosis [IN PERSON]
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}w1wf-lmos2t
 7f-ncw1nq
DESCRIPTION:Join us for this seminar by Andrea Cairoli (Crick Institute) 
 as part of the North West Seminar Series in Mathematical Biology and Dat
 a Sciences. Details of the full series can be found here https://www.cms
 .livjm.ac.uk/APMSeminar/\n\nThe talk will be hosted in person in the Wil
 liamson Building\, Room G.03. For those who cannot attend in person the 
 talk will also be streamed via zoom\, please contact carl.whitfield@manc
 hester.ac.uk or igor.chernyavsky@manchester.ac.uk for the zoom link\, or
  sign up to the mailing list.\n\nAbstract: Cellular tissues form through
  self-organized\, controlled programs of development relying on feedback
  between cellular processes\, tissue-wide properties\, and external cues
 . This complex interplay is exemplified by the metamorphic program the D
 rosophila abdominal epidermis undergo during pupal development. Before m
 etamorphosis\, histoblasts\, progenitor cells of the adult epithelium\, 
 live in dormancy within the nests\, confined regions in the abdomen loca
 ted symmetrically to the dorsal midline\, and surrounded by the larval e
 pithelium. During metamorphosis\, histoblasts proliferate while replacin
 g the larval epidermis\, by coordinating the extrusion of larval cells t
 hrough apoptosis. Histoblasts from the left and right abdominal hemisegm
 ents eventually fuse at the midline to finalize the adult epidermis. How
  the histoblasts regulate their proliferation\, divisions and kinetics\,
  and interact with the larval cells to achieve the correct adult abdomen
  size and the fusion process is largely unknown. In this talk\, I will s
 tudy the morphogenetic process of the abdominal epithelium of Drosophila
  by reconstructing the spatiotemporal dynamic of cell elongation\, area 
 and velocity of the histoblasts and larval cells. I will then recapitula
 te the experimental observations by formulating a continuum model of the
  dynamic of the tissue.\n\nTo subscribe to the mailing list for this eve
 nt series\, please send an e-mail with the phrase “subscribe math-lifesc
 i-seminar” in the message body to listserv@listserv.manchester.ac.uk
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
LOCATION:G.03\, Williamson Building\, Manchester
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