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Can we combine experimental and modelling studies to understand signal regulation in development? Why Notch.

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Dates:8 May 2015
Times:15:00 - 16:00
What is it:Seminar
Organiser:Faculty of Life Sciences
Who is it for:University staff, Current University students
Speaker:Dr Martin Baron
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  • In category "Seminar"
  • In group "(FLS) Celebrating Research Success in FLS"
  • By Faculty of Life Sciences

The next seminar in the ‘FLS Celebrating Research Success' series will be given by Dr Martin Baron, who is a member of the Development Research Theme.

Notch is a highly conserved cell signalling receptor which plays many fundamental roles in development and adult tissue maintenance, with strong links to human disease. My recent work has shown that there is an unexpected diversity of different mechanisms that can lead to Notch activation which involve trafficking of Notch within an endosomal network. I will discuss how this network contributes genetic and environmental robustness to Notch signalling during Drosophila development. I will further highlight how the interplay between experimental and mathematical modelling approaches has enhanced our investigation of this problem.

Speaker

Dr Martin Baron

Organisation: Faculty of Life Sciences

  • http://www.ls.manchester.ac.uk/people/profile/?alias=baronm

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Michael Smith Lecture Theatre
Michael Smith Building
Manchester

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Dr Louise Barnes

louise.m.barnes@manchester.ac.uk

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