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Richard Wilkinson - Uncertainty quantification for heart surgeons

Patterned pufferfish scales demonstrating a Turing pattern in the natural world
Dates:30 November 2020
Times:14:00 - 15:00
What is it:Seminar
Organiser:Department of Mathematics
Who is it for:University staff, External researchers, Current University students
Speaker:Richard Wilkinson
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  • Mathematics in the life sciences
  • Department of Mathematics

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  • In category "Seminar"
  • In group "(Maths) Mathematics in the life sciences "
  • In group "(Maths) Maths seminar series"
  • By Department of Mathematics

(via Zoom) Join us for this seminar by Richard Wilkinson (Nottingham) as part of the North West Seminar Series in Mathematical Biology and Data Sciences. Details of the full series can be found here https://www.cms.livjm.ac.uk/APMSeminar/

Please contact carl.whitfield@manchester.ac.uk for the zoom link, or sign up to the mailing list.

Abstract: Atrial fibrillation (AF) is a type of cardiac arrhythmia that affects about 1 million people in the UK, and is caused when electrical waves in the atria become disorganised, reducing the ability of the heart to pump blood. Catheter ablation is used to remove abnormal tissue, with the aim of stopping the electrical pathways that sustain the arrhythmia. Surgeons must decide which tissue to ‘ablate’ on the basis of limited noisy data: MRI scans of the heart done in advance of the surgery, and the results of electrophysiology studies performed during surgery. About 40% of patients treated for AF go on to suffer atrial tachycardia (another type of arrhythmia) which may then require further surgery (with associated risks and costs).

In this talk, I will discuss ongoing work that aims to combine the available data on a patient with complex simulation models of electrical activation in the atria, using experience learnt from operations on previous patients, to build a personalised digital twin that can be used during a time-pressured surgery to guide the ablation process.

To subscribe to the mailing list for this event series, please send an e-mail with the phrase “subscribe math-lifesci-seminar” in the message body to listserv@listserv.manchester.ac.uk

Speaker

Richard Wilkinson

Role: Professor

Organisation: University of Nottingham

  • https://rich-d-wilkinson.github.io/

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Carl Whitfield

carl.whitfield@manchester.ac.uk

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