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PRODID:-//Columba Systems Ltd//NONSGML CPNG/SpringViewer/ICal Output/3.3-
 M3//EN
VERSION:2.0
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20140522T141703Z
DTSTART:20140613T130000Z
DTEND:20140613T140000Z
SUMMARY:How the mouse gets its tail: role of neuromesodermal stem cell-li
 ke progenitors in axis elongation
UID:{http://www.columbasystems.com/customers/uom/gpp/eventid/}zo5-hs4hds4
 y-7qso94
DESCRIPTION:This seminar is part of the Manchester Tissue Regeneration & 
 Stem Cell Network seminar series.                                       
                                                               The Wilson
  lab identified a bipotent population of progenitors for the anteroposte
 rior axis in mouse\, neuromesodermal (NM) progenitors\, and showed that 
 these cells are bipotent stem cell-like progenitors.  Current research f
 ocuses on the factors that control maintenance and differentiation of th
 ese cells\, using experimental embryology techniques (embryo microdissec
 tion\, grafting and culture)\, as well as cell culture of pluripotent ce
 ll lines\, to investigate whether developmental cues identified in the e
 mbryo can be used to propagate NM progenitor cells in vitro\, and contro
 l their differentiation.  I will present our recent data using in vitro 
 epiblast stem cell lines and embryo micromanipulation to elucidate the r
 ole of Wnt signalling in specifying\, maintaining and directing the diff
 erentiation of these progenitors.
STATUS:TENTATIVE
TRANSP:TRANSPARENT
CLASS:PUBLIC
LOCATION:Lecture Theatre\, Michael Smith Building\, Manchester
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