12:30 – 2:00pm (lunch 12:30 – 1:00pm; presentations 1:00 – 2:00pm)
Michael Smith Lecture Theatre (lunch in lounge area)
Hosted by Institute of Inflammation and Repair and the Wellcome Trust Centre for Cell Matrix Research, Faculty of Life Sciences
About the event:
Dr Adam Reid, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences:
“Peripheral nerve injury – from lab to clinic”
The aim of Adam’s research is to complement his clinical interests in plastic surgery, in particular surgical reconstruction following trauma and disease. He is examining novel interventions in pre-clinical models of peripheral nerve injury and will conduct a NIHR supported first-in-man study on a polymer based nerve conduit in collaboration with School of Materials (UoM) at University Hospital of South Manchester in 2016. Furthermore, he is developing novel applications for adipose-derived stem cells (ASC) in tissue regeneration funded by the Healing Foundation.
Dr Karin Jansen, Ballestrem Lab, Wellcome Trust Centre for Cell Matrix Research, Faculty of Life Sciences:
“Cell-Matrix Adhesions - Molecular Complexes in Control of Axon Outgrowth and Pathfinding”
Karin studies the mechanosensing of neuronal cells. Cells can perceive different kind of signals, for instance, cells can sense chemical signals in terms of binding ligands and mechanical signals in terms of stiffness (termed ‘mechanosensing’). Both signals are vital in determining cell fate. Karin studies how neuronal cells sense changing mechanical signals. Neurons develop dendritic extensions, where one dendrite is significantly longer than the rest (termed the axon). How these axons find their target in vivo remain poorly understood. Karin studies neuronal mechanosensing, with a focus on two core mechanosensing proteins, namely talin and vinculin. Using micro-patterns, the effect of changing ligands as chemical signals are investigated on growth cone advance and directionality, while changing the underlying mechanical cues. Using these techniques, her research hopes to elucidate the underlying mechanisms of neuronal mechanosensing and growth cone advance and directionality.
Who's it for?
The monthly Faculty Research Series events are open to all staff and students from across the Faculty of Medical and Human Sciences and the University, offering an opportunity to celebrate research achievement and stimulate scientific interaction. Each month one host School or Institute from the Faculty will pair with a different School or Institute to highlight and showcase similar topics from different perspectives.
Held on Wednesday lunchtimes, each meeting lasts an hour, including two 20 minute presentations – one from a senior and one from a more junior member of Faculty staff. Each presentation will be followed by a short discussion. A buffet lunch will be available from 12.30. Presentations begin at 1pm.
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See a full list of Faculty Research Series dates.