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MBC Seminar – Prof Roger Gomis, IRB Barcelona “ER+ Breast cancer metastasis cell fate mapping”

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Dates:15 September 2025
Times:14:00 - 15:00
What is it:Seminar
Organiser:Manchester Breast Centre
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MBC Seminar – Prof Roger Gomis, IRB Barcelona “ER+ Breast cancer metastasis cell fate mapping”

Date: Monday 15th September 2025 Time: 14:00 – 15:00 Venue: Oglesby Cancer Research Building Lecture Theatre, 555 Wilmslow Rd, Manchester M20 4GJ Host: Rob Clarke

No sign up needed, just turn up on the day!

Prof Roger R Gomis is an ICREA Research Professor and a member of the Cancer Science Program at the Institute for Research in Biomedicine, Barcelona. He received his PhD in biochemistry from the University of Barcelona in 2002, and was a postdoctoral fellow at Memorial Sloan-Kettering Cancer Center in Prof. Joan Massagué's laboratory. In 2007, he assumed his current position. Since 2018 he is an associate professor at the University of Barcelona. The Gomis laboratory seeks to improve the prognosis, prevention, and treatment of cancer by studying the basic principles underlying the development of this disease. The lab has focused on identifying and functionally validating genes that enable breast and colon cancers to metastasize to clinically relevant sites. In particular, during the last years, the lab strived to unravel the tissue-specific mediators and time dependent components of metastasis processes. The goal is to improve metastasis treatment, with focus in prevention of dissemination. The lab findings have become an objective approach to selection of breast cancer patients for adjuvant bisphosphonates treatment to prevent metastasis (Coleman et al. Lancet Oncol. 2017 and Paterson et al JNCICs 2021, www.inbiomotion.com inbiomotion.com). In addition, the lab has provided insights into how breast cancer metastatic epithelial cells remain latent, by controlling luminal differentiation attributes through epigenetic marks, which limits their initiation and expansion at the metastatic site (Gawrzak et al Nat. Cell Biol. 2018) and how they are licensed for metastasis (Llorente, Blasco et al Nat. Cell. Biol. 2023).

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Oglesby Cancer Research Building
555 Wilmslow Rd
Manchester

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Rebecca Murray

rebecca.murray@manchester.ac.uk

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