GL Brown Prize Lecture 2014 - Porf David Eisner, University of Manchester
Calcium in the heart: from physiology to disease
It is 130 years since Sydney Ringer found that calcium is required for cardiac contraction. Enormous progress has been made recently in unraveling the regulation of calcium but there is much left to do.
In this lecture I will present an overview of cardiac calcium signaling, showing how imaging, electrophysiology, molecular tools and animal models have contributed to our understanding of the physiology. The first half of the talk will concentrate on the simple, yet elegant mechanisms that regulate calcium. The remainder will focus on abnormal calcium regulation and how this can lead to some of the changes seen in heart failure as well as contributing to the origins of cardiac arrhythmias.
Prof David Eisner
Role: GL Brown Prize Lecture 2014
Organisation: Manchester University
Travel and Contact Information
Lecture Theatre 1