Sensing of the environment by the NLRP3 inflammasome
|Starts:||16:00 10 Feb 2016|
|Ends:||17:00 10 Feb 2016|
|What is it:||Seminar|
|Organiser:||Faculty of Life Sciences|
|Who is it for:||University staff, Current University students|
Leaders in Science - The first talk of the series will be delivered by Professor Eicke Latz who is Director of the Institute of Innate Immunity at the University of Bonn in Germany. The title of his talk is ‘Sensing of the environment by the NLRP3 inflammasome’.
Eicke is a world leader in inflammation research, who is renowned for his hypothesis of the inflammasome in Alzheimer’s Disease. He has numerous, seminal Nature papers and is well known for delivering a great lecture. His research profile can be seen here: http://www.iii.uni-bonn.de/en/research/overview_innate_immunity.html.
Recent, highlight publications include:
· Levy M, et al. 2015. Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell. PMID: 26638072
· Netea MG, Latz E, et al. 2015. Innate immune memory: a paradigm shift in understanding host defense. Nat Immunol. PMID: 26086132
· Heneka MT, Golenbock DT and Latz E. 2015. Innate immunity in Alzheimer's disease. Nat Immunol. PMID: 25689443
· Coll RC et al. 2015. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. PMID: 25686105
· Geyer M, Pelka K and Latz E. 2015. Synergistic activation of Toll-like receptor 8 by two RNA degradation products. Nat Struct Mol Biol. PMID: 25650902
Eicke will be hosted by Dr David Brough, who has arranged a schedule for the day.
Organisation: Institute of Innate Immunity, University of Bonn, Germany
Travel and Contact Information
Michael Smith Lecture Theatre
Michael Smith Building