Centre for Biostatistics seminar | How SMART is your study? Designing a trial to obtain quality data about dynamic treatment regimes
|Starts:||15:00 31 Mar 2014|
|Ends:||16:00 31 Mar 2014|
|What is it:||Seminar|
|Organiser:||Institute of Population Health|
|Who is it for:||Alumni, Current University students, General public, University staff|
|Speaker:||Prof Erica Moodie|
Host: Centre for Biostatistics
About the event:
The Centre for Biostatistics have organised a special seminar by Professor Erica Moodie, who is on sabbatical from McGill University at The University of Oxford and will be visiting Manchester.
All are welcome to attend, and no prior registration is required.
Speaker: Prof Erica Moodie, McGill University, Canada
Title: How SMART is your study? Designing a trial to obtain quality data about dynamic treatment regimes
Current practice in randomized trials typically focuses on identifying the single best treatment for a particular condition. Clinical practice, however, has consistently been more concerned with a patient- rather than disease-centric approach. Dynamic treatment regimes are part of a rapidly expanding area of research whereby such personalized treatment strategies can be identified. These methods can lead to improved results over standard 'one size fits all' approaches, and provide a route to formalizing treatment adjustments in an evidence-based manner. In this talk, I will give an introduction to dynamic treatment regimes, focusing primarily on sequential multiple assignment randomized trials (SMARTs), the best means of obtaining high-quality data to determine optimal treatment regimes. I will then demonstrate how, in a pharmacological context, simulations may be used to help narrow the field of potential regimes studied before embarking on a SMART.
Prof Erica Moodie
Role: Associate Professor
Organisation: McGill University, Canada
Travel and Contact Information
Jean McFarlane Building