Can we combine experimental and modelling studies to understand signal regulation in development? Why Notch.
|Starts:||15:00 8 May 2015|
|Ends:||16:00 8 May 2015|
|What is it:||Seminar|
|Organiser:||Faculty of Life Sciences|
|Who is it for:||University staff, Current University students|
|Speaker:||Dr Martin Baron|
The next seminar in the ‘FLS Celebrating Research Success' series will be given by Dr Martin Baron, who is a member of the Development Research Theme.
Notch is a highly conserved cell signalling receptor which plays many fundamental roles in development and adult tissue maintenance, with strong links to human disease. My recent work has shown that there is an unexpected diversity of different mechanisms that can lead to Notch activation which involve trafficking of Notch within an endosomal network. I will discuss how this network contributes genetic and environmental robustness to Notch signalling during Drosophila development. I will further highlight how the interplay between experimental and mathematical modelling approaches has enhanced our investigation of this problem.
Dr Martin Baron
Organisation: Faculty of Life Sciences
Travel and Contact Information
Michael Smith Lecture Theatre
Michael Smith Building