Advances in Biosciences Seminar Series - Dr Paulo Baptista-Ribeiro from QMUL, London, Title: "Regulation of Tissue Growth by Cell Polarity Proteins"
| Dates: | 21 January 2025 |
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| Times: | 13:00 - 14:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Biology, Medicine and Health |
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| Who is it for: | University staff |
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| Speaker: | Dr Paulo Baptista-Ribeiro |
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Introducing the next speaker for the Advances in Biosciences Seminar Series: Dr Paulo Baptista-Ribeiro from QMUL, London, Title: "Regulation of Tissue Growth by Cell Polarity Proteins"
Abstract: How tissue growth is regulated is still one of the long-standing unanswered questions in Biology. Studies in the fruit fly Drosophila melanogaster have identified the evolutionarily conserved Hippo signalling pathway as a master regulator of tissue size. However, its regulation is complex and we still lack knowledge regarding the precise molecular details as to how specific stimuli control tissue growth. One of the main interests in the laboratory is the link between Hippo signalling and the function of cell polarity proteins. We have identified new regulatory mechanisms linking the polarity proteins Fat and Crumbs to Hippo signalling and these will be described during the presentation.
Biography: I completed my undergraduate studies in the Faculty of Sciences of the University of Lisbon, where I studied Microbial Biology and Genetics. I spent my final year in the Faculty of Pharmacy studying cell death in neuronal cells.
I then entered the Gulbenkian PhD Programme in Biomedicine at the Gulbenkian Institute, which included one year of classes and laboratory rotation. This allowed me to undertake my doctoral research at the Institute of Cancer Research, London, supervised by Prof Pascal Meier, in the characterisation of the role of inhibitor of apoptosis proteins in the regulation of cell death and innate immunity.
In 2009, I joined the Dr Nicolas Tapon's laboratory at the Cancer Research UK London Research Insitute, where I studied the mechanisms regulating tissue growth, namely the Hippo tumour suppressor signaling pathway.
In August 2013, I joined Barts Cancer Institute as an Early Career Researcher in the Centre for Tumour Biology and, since 2022, I am a Reader in Cell and Developmental Biology.
Our research group is interested in uncovering the molecular mechanisms regulating tissue growth, invasion, metastasis and tumour heterogeneity using the fruit fly Drosophila melanogaster as a genetically tractable model organism
Speaker
Dr Paulo Baptista-Ribeiro
Role: Dr
Organisation: QMUL, London
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Michael Smith Lecture Theatre
Michael Smith Building
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