Lloyd Bridge -- Modern receptor theory and low-dimensional models for binding and signal transduction in mathematical pharmacology [ONLINE]
| Dates: | 19 June 2024 |
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| Times: | 13:00 - 14:00 |
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| What is it: | Seminar |
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| Organiser: | Department of Mathematics |
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| Who is it for: | University staff, External researchers, Current University students |
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| Speaker: | Lloyd Bridge |
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Join us for this seminar by Lloyd Bridge (Bristol) as part of the North West Seminar Series in Mathematical Biology and Data Science
The talk will be hosted by the University of Liverpool and available to watch via zoom. Please contact carl.whitfield@manchester.ac.uk or mdomijan@liverpool.ac.uk for the link, or sign up to the mailing list.
Title: Modern receptor theory and low-dimensional models for binding and signal transduction in mathematical pharmacology
Abstract: Analytical pharmacology stems from concepts underlying classical receptor theory. Many classical assumptions (e.g. monomeric receptors, and single ligand-induced pathway activation) are insufficient to model, understand and exploit the diversity of cellular signalling of pharmacological interest. Here, we present results from recent interdisciplinary work which updates the classical theory. We further outline new directions in the recognised and growing field of mathematical pharmacology, encompassing detailed cell signalling models and compartment models in pharmacokinetics.
The mathematical modelling and analysis in this talk includes linear and nonlinear ODE models, structural identifiability analysis and asymptotic analysis. The talk is designed to be accessible to graduate students.
To subscribe to the mailing list for this event series, please send an e-mail with the phrase “subscribe math-lifesci-seminar” in the message body to listserv@listserv.manchester.ac.uk
Speaker
Lloyd Bridge
Role: Seior Lecturer
Organisation: UWE Bristol
Travel and Contact Information
