Moving the hands of the clock
| Dates: | 9 June 2015 |
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| Times: | 13:00 - 14:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Life Sciences |
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| Speaker: | Aarti Jagganath |
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This seminar is part of the Future Leaders in Sensory and Computational Neuroscience series - showcasing the best up and coming researchers in the field. Abstract: Most aspects of physiology and behaviour, including the sleep-wake cycle display 24-hour rhythms (circadian rhythms), and these rhythms are being increasingly recognised for their role in maintaining health and wellbeing. Circadian rhythms are driven by a molecular oscillator found in many cell types in the body, which are maintained in synchrony by a master circadian pacemaker located in the suprachiasmatic nuclei (SCN). The SCN is synchronised to the dawn-dusk cycle by photic input from the retina, and my research focusses on elucidating the mechanisms by which light entrains the molecular clock. My talk will summarise our recent work in this area, including characterising retinal pathways that signal light information to the circadian system and transcriptional pathways activated by light within the SCN. Based on these results, we have extended our findings to the identification of novel and tractable signalling pathways by which the clock may be targeted for pharmacological modulation.
Speaker
Aarti Jagganath
Organisation: University of Oxford
Travel and Contact Information
Find event
4.005
AV Hill Building
Manchester
