Centre for Biological Timing Seminar - Systems Biology of Human Sleep/Wake Cycles: Phosphorylation Hypothesis of Sleep by Professor Hiroki Ueda (University of Tokyo and RIKEN)
| Dates: | 12 May 2023 |
|---|
| Times: | 13:00 - 14:00 |
|---|
| What is it: | Seminar |
|---|
| Organiser: | Faculty of Biology, Medicine and Health |
|---|
| Who is it for: | University staff, Current University students |
|---|
| Speaker: | Professor Hiroki Ueda |
|---|
|
Systems Biology of Human Sleep/Wake Cycles: Phosphorylation Hypothesis of Sleep by Professor Hiroki Ueda, the University of Tokyo and RIKEN, Japan.
Further details can be found on the event flyer
Speaker bio
Professor Hiroki R. Ueda, graduate school of medicine, The University of Tokyo.
He graduated from the Faculty of Medicine, the University of Tokyo in 2000, and obtained his Ph.D. in 2004 from the same university. He was appointed as a team leader in RIKEN in 2003. He became a full professor in Graduate School of Medicine, the University of Tokyo in 2013. In 2016, he found the first sleep-promoting kinases, CaMKIIalpha and CaMKIIbeta and proposed phosphorylation hypothesis of sleep that phosphorylation-dependent regulation of Ca2+-dependent hyperpolarization pathway underlies the regulation of sleep homeostasis in mammals. In 2018, he also found the first essential genes of REM sleep, muscarinic receptors M1 and M3. To accelerate these studies, he also invented whole-brain and whole-body clearing and imaging methods called CUBIC as well as the next-generation mammalian genetics such as Triple-CRISPR and ES-mice methods for one-step production and analysis of KO and KI mice without crossing.
Speaker
Professor Hiroki Ueda
Organisation: University of Tokyo and RIKEN
Travel and Contact Information
Find event
Michael Smith Lecture Theatre
Michael Smith Building
Manchester
