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Centre for Biostatistics Seminar

Dates:8 April 2019
Times:14:00 - 15:00
What is it:Seminar
Organiser:Faculty of Biology, Medicine and Health
Who is it for:University staff, Current University students
Speaker:Antonia Marsden
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'PSORT and WORKWELL: some projects from the BCU' - Dr Antonia Marsden

Abstract: In this seminar, I’ll talk about a couple of projects I have worked on and am currently working on post-PHD as part of the Biostats Collaboration Unit.

PSORT is an MRC and industry funded programme aiming to gain a better understanding of determinants of response to biologic therapies for the treatment of moderate-to-severe psoriasis and to provide guidance on the choice of biologic therapy for individual patients. I’ll talk though two projects I’ve been involved in: 1) Identifying demographic, social and clinical predictors of biologic therapy effectiveness using registry data, and 2) Evaluating the impact of a prescribing algorithm whereby patients who initiate a biologic therapy have their drug level assessed at 4 weeks and are switched to a salvage therapy if this drug level is below a specified threshold.

The WORKWELL trial is a Versus Arthritis funded randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis which has recently opened to recruitment. I’ll give an overview of the study and talk about some of the strengths and challenges in the design and analysis of the trial including the randomisation method and the complex nature of the intervention.

Speaker

Antonia Marsden

Role: Research Associate in Biostatistics

Organisation: School of Health Sciences

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Jean McFarlane Building
Oxford Rd
Manchester

 

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