Regulation of chemokine function by atypical chemokine receptor
Professor Gerard Graham has a long-standing interest in chemokines and their receptors and has been working in this field for 18 years.
Current research is focused on the role of CXC chemokines in haemopoietic stem cell mobilisation, septic shock and psoriasis. He is also working on the ability of chemokine receptors to be used as therapeutic targets.
If you would like to meet Professor Graham please contact elaine.bignell@manchester.ac.uk
Hansell, C. A.H. et al. (2018) The atypical chemokine receptor, Ackr2, constrains NK cell migratory activity and promotes metastasis. Journal of Immunology,(doi:10.4049/jimmunol.1800131)
Castanheira, F. V. E. S. et al. (2018) The atypical chemokine receptor ACKR2 is protective against sepsis. Shock, 49(6), pp. 682-689.
Shams, K., Kurowska-Stolarska, M. , Schütte, F., Burden, A. D., McKimmie, C. S. and Graham, G. J. (2018) MicroRNA-146 and cell trauma down-regulate expression of the psoriasis-associated atypical chemokine receptor ACKR2. Journal of Biological Chemistry, 293(8), pp. 3003-3012.
