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The 695th Lord Mayor's Lectures: Computational Medicine and Digital Twins Improving Medical Care, with Prof Alex Frangi

Dates:12 January 2024
Times:11:00 - 12:00
What is it:Seminar
Organiser:The Christabel Pankhurst Institute
Who is it for:University staff, External researchers, Adults, Alumni, Current University students, General public
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  • In category "Seminar"
  • By The Christabel Pankhurst Institute

Prof Alex Frangi, Director of the Christabel Pankhurst Institute, and the Bicentennial Turing Chair for Computational Medicine, will speak at the Lord Mayor’s Lectures Series next week about computational medicine and digital twins in healthcare.

Novel medical technologies are being introduced at unprecedented rates, demanding scientific evidence of their safety and efficacy at an unprecedented pace to ensure patient safety and benefit. With success in both in-vitro/in-vivo studies, products are tested on clinical trials assessing use in humans. Predicting low-frequency side effects has been difficult because such side effects may not become apparent until many patients adopt the treatment. When medical devices fail at later stages, financial losses can be catastrophic. Testing on many people is costly, lengthy, and sometimes implausible (e.g., paediatric patients, rare diseases, and underrepresented or hard-to-reach ethnic groups).

Computational Medicine underpins In-silico trials (IST), i.e., computer-based trials of medical products performed on populations of digital twins (aka virtual patients). Computer models/simulations are used to conceive, develop, and assess devices with the intended clinical outcome explicitly optimised from the outset (a-priori) instead of tested on humans (a-posteriori). This will include testing for potential risks to patients (side effects) and exhaustively exploring medical device failure modes before being tested in human clinical trials. In-silico evidence is still consolidating but is poised to transform how health and life sciences R&D and regulations are conducted. UK can take a leadership position in in-silico trials, which would cement its position as a global leader in health and life sciences, help drive the UK economy and provide UK citizens with early access to innovative health products.

The Rt Hon the Lord Mayor Alderman Professor Michael Mainelli is pleased to extend an invitation to all to participate in “Knowledge Miles: The Lord Mayor's Lectures”, an online webinar series exploring the connections of the Square Mile and how its knowledge clusters are addressing diverse global challenges.

Link to register: https://register.gotowebinar.com/register/2743880080838287968

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