Regenerative medicine by somatic stem cells: the paradigm of epithelial stem cells
| Dates: | 27 February 2014 |
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| Times: | 12:00 - 13:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Life Sciences |
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| Who is it for: | University staff, Current University students |
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| Speaker: | Michele De Luca |
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This seminar is part of the Special seminar series Prof. De Luca is internationally recognized as a leading scientist in stratified epithelial stem cell biology aimed at clinical application in regenerative medicine. Prof. De Luca played a pivotal role in epithelial stem cell-mediated cell therapy and gene therapy. Beside his pioneering work on the use of human epidermal stem cell cultures in life-saving treatment of massive full-thickness burns and in repigmentation of stable vitiligo and piebaldism, he was first in establishing human limbal stem cell culture aimed at corneal regeneration in patients with severe limbal stem cell deficiency. This treatment leads to recovery of vision in patients with poor alternative therapy. Prof. De Luca is currently coordinating the first (successful) ex-vivo epithelial stem cell-mediated gene therapy clinical trial for the gene therapy of genetic skin diseases as Junctional Epidermolysis Bullosa. Prof. De Luca is also studying molecular mechanisms regulating long term proliferative potential, clonal evolution and mitotic quiescence of epithelial stem cells.
Speaker
Michele De Luca
Role: Professor
Organisation: University of Modena
Travel and Contact Information
Find event
1.006
AV Hill Building
Manchester
