Dr Jeffrey Kelu: Circadian regulation of protein turnover by muscle peripheral clock
| Dates: | 18 October 2024 |
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| Times: | 13:00 - 14:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Biology, Medicine and Health |
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| Who is it for: | University staff, Adults, Current University students, General public |
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| Speaker: | Dr Jeffrey Kelu |
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We are excited to announce that on Friday the 18 October, we are hosting a seminar by Dr. Jeffrey Kelu about his work entitled 'Circadian regulation of protein turnover by muscle peripheral clock'.
Dr. Kelu obtained his PhD from Hong Kong University of Science and Technology, and now works as a research associate in the Hughes lab of the Randall Centre of Cell and Molecular Biophysics, King’s College London. Dr. Kelu is currently investigating the cellular and molecular mechanisms governing the growth of skeletal muscle, with a specific focus on circadian clock regulation. Using zebrafish models, he discovered that in zebrafish larvae muscle grows faster in the day than at night, a phenomenon that is paralleled by higher diurnal protein anabolism and nocturnal protein catabolism. Importantly, he demonstrated that these rhythmic processes continue to occur under the absence of physical activity and feeding behaviour, suggesting their direct regulation by the intrinsic circadian clock. His findings significantly advance understanding of the regulation of muscle metabolism by the circadian clock. Deeper study will increase understanding of the effects of circadian rhythm disturbance, as seen in shift-work and sleep deprivation, on muscle maintenance and health.
This session will take place on Friday, 18 October, 1-2 pm in the Michael Smith Lecture Theatre.
Sign up for free using Eventbrite.
Speaker
Dr Jeffrey Kelu
Role: Research Associate
Organisation: Hughes lab of the Randall Centre of Cell and Molecular Biophysics, King’s College London
Travel and Contact Information
Find event
Michael Smith Lecture Theatre
Michael Smith Building
Manchester
