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In vivo Tissue Reprogramming Seminar - In vivo Tissue Reprogramming Seminar

Dates:14 March 2023
Times:11:00 - 12:00
What is it:Seminar
Organiser:Faculty of Biology, Medicine and Health
Who is it for:University staff
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  • By Faculty of Biology, Medicine and Health

Abstract:

Addressing the notion of functional tissue reprogramming in vivo. Such reprogramming happens under immune surveillance and achieves desired functional gains at the system level without the need for any tissue grafting or cell transplantation.

In our laboratories, such reprogramming is achieved by tissue nano-transfection technology or TNT. This tissue nano-transfection (TNT) approach allows direct cytosolic delivery of reprogramming factors by applying a highly intense and focused electric field through arrayed nanochannels, which benignly nanoporates the juxtaposing tissue cell membranes and electrophoretically drives reprogramming factors into the tissue. Emphasis will be placed on vasculogenic reprogramming of the skin with other examples including myogenic, neurogenic, and neurotrophic outcomes.

The speaker Professor Chandan K Sen (H-index 109) is a Distinguished Professor at the Indiana University School of Medicine and a Professor at the Weldon School of Biomedical Engineering at Purdue. Dr. Sen directs the Indiana Center for Regenerative Medicine and Engineering.

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Lecture Theatre
Michael Smith Building
Manchester

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Annette Barber

annette.barber@manchester.ac.uk

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