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Generation of stable cartilage by bone marrow derived Mesenchymal Stem Cells

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Dates:19 February 2016
Times:14:00 - 15:00
What is it:Seminar
Organiser:Faculty of Life Sciences
Who is it for:University staff, Current University students
Speaker:Professor Gerjo van Osch
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  • In category "Seminar"
  • In group "(FLS) Manchester Tissue Regeneration and Stem Cell Network Seminar Series"
  • By Faculty of Life Sciences

Part of the Manchester Tissue Regeneration & Stem Cell Network Seminar Series. Sponsored by PCR Biosystems

Bone marrow derived Mesenchymal Stem Cells (BMSC) are known to have chondrogenic capacity. However, the use of BMSCs for repair of cartilage defects is associated with some drawbacks. We are dealing with a heterogeneous population that loses its differentiation capacity during cell expansion. Moreover, once differentiated into chondrocytes they terminally differentiate and produce hypertrophic cartilage that is transformed into bone in vivo. In our research we try to apply principles of embryonic development and tissue engineering to overcome these problems. The lecture will give an overview of our recent and on-going work in this field.

Speaker

Professor Gerjo van Osch

Organisation: Universitat Wurzburg

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Michael Smith Lecture Theatre
Michael Smith Building
Manchester

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Charlotte Houghton

0161 275 5360

charlotte.houghton@manchester.ac.uk

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