Tumour adaptability in endocrine treated breast cancer
Dates: | 4 February 2014 |
Times: | 16:00 - 17:00 |
What is it: | Seminar |
Organiser: | Faculty of Life Sciences |
Speaker: | Leonie Young |
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In breast cancer, a significant number of endocrine treated patients develop recurrent disease. The ability of a tumour to adapt and evade endocrine therapy, though clinically recognised, remains poorly understood. Our group use discovery and molecular studies along with in vivo and clinical models to investigate signalling pathways central to tumour adaptability. We have observed that endocrine therapy can directly contribute to metastasis in resistant tumours and that extracellular matrix signalling network are switched on at metastatic sites following prolonged endocrine treatment.
Speaker
Leonie Young
Role: Professor
Organisation: Breast Cancer Ireland
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Holt Major, Paterson Institute
Wilmslow Road
Manchester