Manchester Infection Seminar Series 2019 - 'Adventures with TB: what a smart pathogen can tell us about the immune system'
| Dates: | 26 April 2019 |
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| Times: | 12:00 - 13:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Biology, Medicine and Health |
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| Who is it for: | University staff, Adults |
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Professor Andrea Cooper
University of Leicester
Adventures with TB: what a smart pathogen can tell us about the immune system
Please join us for Andrea’s talk, on Friday the 26th of April, AV Hill 1.006, 12:00.
Andrea received her Doctoral degree from The London School of Hygiene and Tropical Medicine UK, where she investigated the interaction between macrophages and protozoan parasites of the genus Leishmania. Moving to the National Institutes of Health in Bethesda, USA, she expanded her investigation of leishmaniasis to include the T cell response of patients suffering from cutaneous, mucocutaneous and visceral forms of the disease. Andrea then moved to the Mycobacterial Research Labs at Colorado State University and began studying the protective immune response to Mycobacterium tuberculosis. Prior to her move to the University of Leicester, Andrea was at the Trudeau Institute, Inc. for 12 years, where she held the E.L. Trudeau Chair which allowed her to study the cellular immune response to M. tuberculosis. Andrea is the part of the MRC Infection and Immunity board as deputy chair.
The goal of Andrea’s programme is to define the mechanisms which mediate initiation, expression and regulation of immunity within the lung and her research is currently focusing on the role of lymphocyte priming in prolonged expression of immunity within an inflamed lung environment. The infection model of choice is mycobacterial challenge through droplet particles to the alveolar tissue in the lung. This model uses a low dose challenge, allowing for very early immune-mediated events in the lung tissue to be dissected with regard to kinetics, location and the contribution of specific cell types to immunity. Furthermore, her laboratory is also examining the role of neonatal exposure to bacterial products as a factor which impacts these early responses to mycobacterial infection in the adult. These studies contribute to the development of working models of individual susceptibility to lung disease and to the development of rationally designed interventions.
If you would like to meet with Andrea please contact margherita.bertuzzi@manchester.ac.uk. You are also welcome to join us for lunch at Hickmans.
Travel and Contact Information
Find event
Room 1.006
AV Hill Building
Manchester
