SPECIAL DMDS Divisional Seminar – Venue: Michael Smith Lecture Theatre
Date: Monday 18 November 2019
Venue: Michael Smith Lecture Theatre
SPECIAL DMDS Divisional Seminar:
Benjamin Fairfax – “Deciphering the response to Immune Checkpoint Blockade in patients: insights from analysis of the TCR repertoire.”
Welcome Clinical Fellow, Hon. Consultant Medical Oncologist & Principal Investigator, Department of Oncology, MRC Weatherall Institute for Molecular Medicine, University of Oxford, UK.
Here are some of Benjamin’s most important publications:
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele.
Al-Mossawi H, Yager N, Taylor CA, Lau E, Danielli S, de Wit J, Gilchrist J, Nassiri I, Mahe EA, Lee W, Rizvi L, Makino S, Cheeseman J, Neville M, Knight JC, Bowness P, Fairfax BP. Nat Commun. 2019 Oct 8;10(1):4575. doi: 10.1038/s41467-019-12393-1.
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
Fairfax BP, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight JC.
Science. 2014 Mar 7;343(6175):1246949. doi: 10.1126/science.1246949.
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles.
Fairfax BP, Makino S, Radhakrishnan J, Plant K, Leslie S, Dilthey A, Ellis P, Langford C, Vannberg FO, Knight JC.
Nat Genet. 2012 Mar 25;44(5):502-10. doi: 10.1038/ng.2205.