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Advances in Biosciences Seminar Series - Professor Ewa Paluch, University of Cambridge. Title: “Cross-talk between cell mechanics, cell shape and cell fate”

Dates:4 March 2025
Times:13:00 - 14:00
What is it:Seminar
Organiser:Faculty of Biology, Medicine and Health
Who is it for:University staff
Speaker:Ewa Paluch
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Introducing the next speaker for the Advances in Biosciences Seminar Series: Professor Ewa Paluch, Department of Physiology, Development and Neuroscience, University of Cambridge.

Hosted by Dr Shane Herbert and Sarah Woolner

Title: “Cross-talk between cell mechanics, cell shape and cell fate”

Abstract: A precise control of cell morphology is key for cell physiology, and cell shape deregulation is at the heart of many pathological disorders. Furthermore, transitions in cellular fate and state are often associated with changes in cell shape, and strong evidence points to the existence of feedbacks between mechanics, morphology and fate decisions. Cell morphology is intrinsically controlled by mechanical forces acting on the cell surface, to understand shape it is thus essential to investigate the regulation of cellular mechanics. I will discuss how cellular mechanical properties drive cellular shape changes, and the cross-talk between mechanics and state in cellular transitions.

Speaker Bio: Ewa Paluch graduated in Physics from the Ecole Normale Supérieure in Lyon in 2001 and did a PhD in Biophysics at the Curie Institute in Paris between 2001 to 2005. She started her research group in 2006 at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, as a joint appointment with the IIMCB in Warsaw. In 2013, she was appointed Professor of Cell Biophysics at the MRC LMCB, University College London. From 2014 to 2018, she also headed the new UCL Institute for the Physics of Living Systems, which promotes collaborations between physicists and biologists at UCL. In 2018 she was elected Chair of Anatomy at the University of Cambridge. Ewa is the 19th Professor of Anatomy at Cambridge, and the first woman to hold this Chair in its 300-year history. She has received a number of awards, including the Hooke Medal from the British Society for Cell Biology in 2017, the Blavatnik Award for Young Scientists in the UK in 2019, and the DGZ Carl Zeiss Lecture Award in 2022. She became Fellow of Trinity College Cambridge, and was elected EMBO member in 2018. Ewa's lab combines molecular and cell biology, biophysics, quantitative imaging and modelling to investigate the principles underlying cellular morphogenesis. The lab’s research directions span cell surface mechanics regulation, the control of cell shape during cell division and migration, and the cross-talk between cell mechanics, cell shape and cell fate.

Lab website: https://paluchlab.uk

Speaker

Ewa Paluch

Role: Professor

Organisation: University of Cambridge.

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