A Tale of Two Cycles: circadian rhythms in mammals and respiratory oscillations in yeast
| Dates: | 6 May 2015 |
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| Times: | 13:00 - 14:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Life Sciences |
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| Who is it for: | University staff |
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| Speaker: | Helen Causton |
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Circadian rhythms driven by biological clocks are found in across the animal and plant kingdoms and allow an organism to coordinate
its internal metabolic state with that of the external environment. Despite the importance and widespread nature of these rhythms and
the selective advantage they confer, the primordial mechanism has been hard to dissect as clock proteins do not appear to be conserved,
mammalian systems have multiple clocks and few simple model organisms are available. We have shown that short period respiratory
oscillations in yeast share a number of properties with circadian rhythms: both are redox cycles interwoven with cellular metabolism that
coordinate with the cell division clock. This data points to a common mechanism that drives both ultradian and circadian oscillations and
raises questions about the origins of biological timekeeping.
Speaker
Helen Causton
Organisation: Department of Biological Sciences, Columbia University, New York
Travel and Contact Information
Find event
Michaal Smith Lecture Theatre
Michael Smith Building
Manchester
